@guac · a year ago

How CRISPR is tackling the troubling immune response that’s plagued gene therapy until now

published 9/12/2020


The Conversation


One of the major challenges facing gene therapy — a way to treat disease by replacing a patient’s defective genes with healthy ones — is that it is difficult to safely deliver therapeutic genes to patients without the immune system destroying the gene, and the vehicle carrying it, which can trigger life-threatening widespread inflammation. Three …